XXY+Syndrome

By Ivan Wolansky


 * __What is XXY Syndrome and what does it cause?__**

XXY Syndrome or Klinefelter's Syndrome is a genetic disease in which a male has an extra X chromosome. This can also be in a variation of the disease which is XXYY Syndrome. This causes the male to have a small penis and (or) testicles. It also causes the male to have slightly developed breast and underdevelpoed testicles.

__**What causes XXY Syndrome?**__

XXY Syndrome is caused by you recieving 2 X chromosomes from your mother. It's caused when something happens during Meiosis I when a homologus pair fails to seperate. It could also occur when sister chromatids fail to seperate during Meiosis II. This happens with other homologus pairs too for many other genetic diseases. XXYY Syndrome is again very similar except the Y and X fail to seperate. 1 out of every 500 males have an extra X chromosome but only 1 out of every 1000 actually have XXY syndrome.

__**What are the signs and symptoms of XXY Syndrome?**__

Signs of XXY Syndrome are a lanky, youthful build and a rounded face with some more breast tissue than normal. More signs are small penis and small testicles. Another sign is that is causes the man to have low serum testosterone levels but high serum folliclestimulating hormone and luteinizing hormone. Another sign or symptom is that you could develop male breast cancer, germ cell tumors and osteoporosis. A positive symptom about XXY syndrome is that there are some recessive X linked diseases that are cancelled out by the other X.